Adaptive Platform Treatment Trial for Outpatients with COVID-19 (Adapt Out COVID)

The primary outcome measures in the phase II evaluation will be duration of symptoms, SARS-CoV-2 RNA below lower limit of quantification by nasopharyngeal (NP) swabs, and safety. The primary outcome measures in the phase III evaluation will be the composite of hospitalization due to any cause or death due to any cause, and safety.