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The purpose of the MOST study is to determine whether argatroban and/or eptifibatide is superior to placebo in improving 90-day modified Rankin scores (mRS) in acute ischemic stroke (AIS) patients treated with IV rt-PA (0.9mg/kg) or TNK (0.25mg/kg) within three hours of symptom onset.
Principal Investigator | Patricia Fernandez, M.D. |
Co-PI | Esmeralda Cordoso-Mendoza |
Sponsor | Washington University School of Medicine / National Institute of
Neurological Disorders and Stroke (NINDS) |
Type of Trial | Interventional |