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DHRHealth Institute for Research and Development

Clinical Trial

Pragmatic Evaluation of Events And Benefits of Lipid-lowering in Older Adults (PREVENTABLE)

Study Status:

Open for enrollment

Contact Information:

(956) 362-2391

Please contact us for more information or to learn if you are eligible to participate.

Study Purpose:

PREVENTABLE is one of the largest research studies in older adults. The purpose is to learn if taking a statin could help older adults live well for longer by preventing dementia, disability, or heart disease. A statin is a commonly used drug to lower cholesterol.

Participants will be randomized 1:1 to atorvastatin 40 mg or placebo. This large study conducted in community-dwelling older adults without cardiovascular disease (CVD) or dementia will demonstrate the benefit of statins for reducing the primary composite of death, dementia, and persistent disability and secondary composites including mild cognitive impairment (MCI) and cardiovascular events.

Information: 

Principal Investigator
Sohail Rao, M.D.
Co-PI
Esmeralda Cordoso-Mendoza
Sponsor
Duke University / National Institute on Aging (NIA)
Type of Trial
Interventional
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